Graves Ophtalmic Disease
Graves-ova bolest podrazumjeva pojačano djelovanje štitatste zlijezde, odnosno hipertireoidizam. Danas se smatra da je bolest immune prirode, da u tijelu nastaju antitijela koja ošteċuju pojedina tkiva organizma, pored tireoidee i neke strukture oka, posebno očne mišiċe I masno tkivo očne duplje. U Evropi se vise koristi naziv Bazedovljeva bolest (vidi wikipedia ).
Ako bolest nije praċena poveċanjem količine hormona štitaste žlijezde u krvi, nego ako samo postoje očne promjene, onda govorimo o očnoj Graves-ovoj bolesti.
Promjene na očima podrazumjevaju široku skalu, prema stepenu ošteċenosti. Najblaži oblici su crvenilo očiju i vidni diskomfor, pa onda povlačenje gornjeg kapka i otkrivanje beonjače u gornjem dijelu oka, pa do različitih stepenova izbočenosti (egzoftalmusa) očiju. Najtezi su poremecaji ostecenja vidnog zivca usljed pritiska masnog tkiva ocne duplje.
Ovdje donosimo ispovijest jedne bolesnice koja pati od ove bolesti.
When I was diagnosed with Graves' disease in February 1990 I had never even heard of the name. Months later I would hear reports of President Bush and Barbara Bush being diagnosed with the same disease. I joked about having a presidential disease and felt some comfort in knowing that the Bushes were receiving treatment at the Mayo Clinic, also. They recovered gracefully. Little did I know what the future had in store for me.
Graves' disease may be the most common cause of hyperthyroidism, or overactivity of the thyroid gland. Although there’s no known cause of Graves’ disease, the patient’s immune system produces antibodies which attack various parts of the body: the thyroid gland, the eye muscles, and/or the skin of the lower legs. Options for treating Graves’ disease problems include antithyroid drugs (ATDs), radioactive iodine (RAI), and surgery. None of these treatments eliminate the Graves' antibodies, so doctors treat the symptoms caused by the antibodies.
Graves' disease mostly affected my eyes, which became irritated, light-sensitive, red, swollen, and bulging. The doctors at the Mayo Clinic in Rochester, MN, became my lifeline for a while. Shortly after diagnosis, I received the radioactive iodine treatment to "kill" part of my thyroid and decrease the production of my thyroid hormones. When I entered the hypothyroidism stage, I was put on a daily dose of Synthroid, a thyroid hormone replacement drug. That was the easy part - getting my eyes back to normal was a different story. In 1993 I had orbital decompression surgery, extraocular muscle surgery, and eyelid retraction surgery on both eyes. These procedures brought relief, and I started to look like myself again. Because my eyes still weren't closing completely, I had another eyelid retraction surgery done on each eye in 1996. Today, I might look a little sleepy, but my eyes are pretty much back to normal.
I share my story in hopes that I can help someone else who is battling this disease. I have met many new friends through the Graves' Disease Bulletin Board, something I wish I’d had at the time of my diagnosis.
Sarajevski medicinari,zlatna generacija